Education (last 5 years)

A. Doctoral Thesis

B. Master's Thesis

• Title: Molecular mechanisms of mitochondrial dysfunction in diseases such as cancer or Parkinson. University of Córdoba, University Master's Degree in Translational Biomedical Research. Student: Agustina Lavin. Supervisors: C. Alicia Padilla Peña and Raquel Requejo Aguilar. Defense date: June 2019.
• Title: Mitochondrial dysfunction and metabolic alterations at the origin of Parkinson's disease. University of Córdoba, University Master's Degree in Translational Biomedical Research. Student: Arancha Mora Rubio. Supervisors: Raquel Requejo Aguilar and José Antonio Bárcena. Defense date: September 2018.
• Title: Glycolytic alterations in HepG2 cells that overexpress NOS3. Cellular role of redoxin systems. University of Córdoba, University Master's Degree in Biotechnology. Student: Lidia Pozo Aranda. Supervisors: Raquel Requejo Aguilar and C. Alicia Padilla Peña. Defense date: September 2017.
• Title: Mitochondrial dysfunction and metabolic alterations at the origin of Parkinson's disease. University of Córdoba, University Master's Degree in Biotechnology. Student: Cristina Morilla Lomeña. Supervisors: Raquel Requejo Aguilar and José Antonio Bárcena. Defense date: September 2017.
• Title: Redox changes in specific proteins associated with redoxin-dependent tumor cell proliferation. University of Córdoba, University Master's Degree in Biotechnology. Student: María José López Grueso. Supervisors: José Antonio Bárcena and Raúl González Ojeda. Defense date: 22/07/2015.
• Title: Fasudil and Curcumin nanoconjugates as promising tools in protection and regeneration of neural cells: A pilot study. Centro de Investigación Príncipe Felipe, Valencia. Student: Alba Guijarro Belmar. Supervisors: Raquel Requejo Aguilar and Victoria Moreno Manzano.  Date of reading: 12/06/2015.

C. Dirección de Trabajos de Fin de Grado

• Title: Structure-function relationship in a multidomain protein. Student: Alejandra Díaz Chacón. Supervisors: J. Antonio Bárcena Ruiz and Marta Rosel Pérez Morales. Course: 2019-20. Degree: Biochemistry.
• Title: Human glutathione transferase π (GST-π): cloning, expression, purification and characterization of the recombinant protein. Student: Antonio Moreno Rodríguez. Supervisors: C. Alicia Padilla Peña and Raquel Requejo Aguilar. Course: 2019-20. Degree: Biochemistry.
• Title: Obtaining and characterization by immortalization of a fibroblast line mutant for Pink1 protein. Student: Yajaira Feller Sánchez. Supervisors: J. Antonio Bárcena Ruiz and Raquel Requejo Aguilar. Course: 2019-20. Degree: Biochemistry.
• Title: Role of intestinal microbiota in the development of neurodegenerative diseases. Student: Blanca Morillo-Velarde Castro. Supervisors: Raquel Requejo Aguilar. Course: 2019-20. Degree: Nursing.
• Title: Nitrates, nitrites and nitric oxide and their effects on the body through the nutitional pathway. Student: Manuel León Baena. Supervisors: José Peinado Peinado. Course: 2019-20. Degree: Nursing
• Title: Transfection and characterization of a Prdx6 knockout human hepatoblastoma cell line (HepG2) with a vector expressing a mutant isoform of Prdx6(S32A). Student: Manuel Alejandro Jiménez Vaquero. Supervisors: C. Alicia Padilla Peña and MªJosé López Grueso. Course: 2018-19. Degree: Biochemistry.
• Title: Conformational flexibility in proteins: computational analysis of the synergic folding of intrinsically unstructured proteins. Student: José Carlos Casas Martínez. Supervisors: J. Antonio Bárcena Ruiz and Marta Rosel Pérez Morales. Course: 2018-19. Degree: Biochemistry.
  
• Title: Intercommunication betwee PRDX6 and DJ-1 antioxidant systems: Consequences for Parkinson's disease. Student: Laura Cuesta López. Supervisors: Raquel Requejo Aguilar. Course: 2018-19. Degree: Biochemistry.
• Title: Ketogenic diet as a treatment of refractory epilepsy in pediatrics. Nursing scope. Student: Raquel Campos González. Supervisors: Raquel Requejo Aguilar. Course: 2018-19. Degree: Nursing.
• Title: Pathologies related to aging: relationship and common causes. Student: Elena López Gallurt. Supervisors: Raquel Requejo Aguilar. Course: 2018-19. Degree: Nursing.
• Title: Study of protein-kinases involved in cell signaling in Parkinson's disease. Student: Lourdes García Ortega. Supervisors: Raquel Requejo Aguilar. Course: 2017-18. Degree: Biochemistry.
• Title: Construction and characterization of a human hepatoblastoma cell line (HepG2) lacking peroxiredoxin 6 using the CRISPR/Cas9 methodology. Student: Álvaro Fernando García Jiménez. Supervisors: C. Alicia Padilla Peña. Course: 2017-18. Degree: Biochemistry.
• Title: Importance of the structure-activity relationship of drugs in their mechanism of action: study through modeling and molecular docking. Student: Raquel González Martos. Supervisors: J. Antonio Bárcena y Marta R. Pérez Morales. Course: 2017-18. Degree: Biochemistry.
• Title: Metabolic changes associated with the DJ-1 protein related to Parkinson´s disease in a mouse model. Student: Silvia Calero Pérez. Supervisors: J. Antonio Bárcena Ruiz and Raquel Requejo Aguilar. Course: 2016-17. Degree: Biochemistry.
• Title: Rescue of the doble mutant of S. cerevisiae ∆grx2∆trx3 with the gene encoding mitochondrial thioredoxin (trx3) cloned in plasmid pCM188. Student: Daniel J. Lagal Ruiz. Supervisors. C.Alicia Padilla Peña. Course: 2016-17. Degree: Biochemistry.
• Title: Human thioredoxin 1 (Trx1): cloning, expression, purification and characterization of the recombinant protein. Student: Elvira Rodríguez Vázquez. Supervisors: C. Alicia Padilla Peña. Course: 2016-17. Degree: Biochemistry.
• Title: Modelling of a protein of special biological interest and study of its interaction with ligands by molecular docking. Student: Miguel Ángel Palacios Pedrero. Supervisors: J. Antonio Bárcena Ruiz and Marta Rosel Pérez Morales. Course: 2016-17. Degree: Biochemistry.
  
• Title: Human peroxiredoxin 6 (Prdx6): cloning, expression, purification and characterization of the recombinant protein. Student: Araceli Aguilar González. Supervisors: C. Alicia Padilla Peña. Course: 2015-16. Degree: Biochemistry.
• Title: Regulation of cellular antioxidant systems by mitochondrial ROS and its relevance to Parkinson's disease in a yeast model. Student: Irene Sánchez de Puerta de Miguel. Supervisors: J. Antonio Bárcena Ruiz and Raquel Requejo Aguilar. Course: 2015-16. Degree: Biochemistry.
• Title: Modelling of a protein of special biological interest and theoretical study of its interaction and coupling with substrates, inhibitors and cofactors. Student: Julia Pérez Saavedra. Supervisors: J. Antonio Bárcena Ruiz and Marta Rosel Pérez Morales. Course: 2015-16. Degree: Biochemistry.
  
• Title: Using Garcinia Cambogia as a supplement in the weight loss process. Student: Vanesa Hidalgo Digo. Supervisors: José Peinado Peinado. Course: 2015-16. Degree: Nursing.
• Title: Molecular bases of winw aroma. Student: Noemi Carnerero Ruiz. Supervisors: José Peinado Peinado and Nieves López de Lerma. Course: 2015-16. Degree: Chemistry.
• Title: Evolution and aromatic improvement in wines with Pedro Ximénez variety grape. Student: Lorite Casado Muñoz. Supervisors: José Peinado Peinado and Mª Teresa García Martínez. Course: 2015-16. Degree: Enology.

D. Becas de Iniciación a la Investigación

Beca de Colaboración del Ministerio de Educación y Ciencia: Silvia Daza Dueñas (2019-2020); Manuel Alejandro Jiménez Vaquero (2018-2019); Laura Cuesta López (2018-2019); Álvaro Fernando García Jiménez (2017-2018); Lourdes García Ortega (2017-2018); Daniel J. Lagal Ruiz (2016-2017); Araceli Aguilar González (2015-2016).

Becas Semillero de Investigación de la Universidad de Córdoba: Mª José López Grueso (2016); Elvira Rodríguez Vázquez (2017).